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Towards an Artificial Golgi: Redesigning the Biological Activities of Heparan Sulfate on a Digital Microfluidic Chip

Using digital microfluidics, recombinant enzyme technology, and magnetic nanoparticles, we have created a functional prototype of an artificial Golgi organelle. Analogous to the natural Golgi, which is responsible for the enzymatic modification of glycosaminoglycans immobilized on proteins, this art...

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Detalhes bibliográficos
Main Authors: Martin, Jeffrey G., Gupta, Megha, Xu, Yongmei, Akella, Srinivas, Liu, Jian, Dordick, Jonathan S., Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765222/
https://ncbi.nlm.nih.gov/pubmed/19591465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja903038d
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