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Current Concepts of Mechanisms in Drug-Induced Hepatotoxicity

Drug-induced liver injury (DILI) has become a leading cause of severe liver disease in Western countries and therefore poses a major clinical and regulatory challenge. Whereas previously drug-specific pathways leading to initial injury of liver cells were the main focus of mechanistic research and c...

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Detalhes bibliográficos
Main Authors: Russmann, Stefan, Kullak-Ublick, Gerd A, Grattagliano, Ignazio
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765083/
https://ncbi.nlm.nih.gov/pubmed/19689281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/092986709788803097
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