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The conserved Est1 protein stimulates telomerase DNA extension activity
The first telomerase cofactor identified was the budding yeast protein Est1, which is conserved through humans. While it is evident that Est1 is required for telomere DNA maintenance, understanding its mechanistic contributions to telomerase regulation has been limited. In vitro, the primary effect...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765079/ https://ncbi.nlm.nih.gov/pubmed/19805136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905703106 |
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