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Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

Vertebrate vision is maintained by the retinoid (visual) cycle, a complex enzymatic pathway that operates in the retina to regenerate the visual chromophore, 11-cis-retinal. A key enzyme in this pathway is the microsomal membrane protein RPE65. This enzyme catalyzes the conversion of all-trans-retin...

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Bibliografiska uppgifter
Huvudupphovsmän: Kiser, Philip D., Golczak, Marcin, Lodowski, David T., Chance, Mark R., Palczewski, Krzysztof
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765077/
https://ncbi.nlm.nih.gov/pubmed/19805034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906600106
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