Phenylmethimazole Decreases Toll-like Receptor 3 and Non-Canonical Wnt5a Expression in Pancreatic Cancer & Melanoma Together with Tumor Cell Growth & Migration

PURPOSE: To evaluate whether (i) Wnt5a expression in pancreatic cancer and malignant melanoma cells might be associated with constitutive levels of Toll-Like Receptor (TLR)-3 and/or TLR3 signaling (ii) phenylmethimazole (C10), a novel TLR signaling inhibitor, could decrease constitutive Wnt5a and TL...

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Hauptverfasser: Schwartz, Anthony, Malgor, Ramiro, Dickerson, Eric, Weeraratna, Ashani, Slominski, Andrzej, Wortsman, Jacobo, Harii, Norikazu, Kohn, Aimee D., Moon, Randall T., Schwartz, Frank, Goetz, Doug, Kohn, Leonard D, McCall, Kelly D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765042/
https://ncbi.nlm.nih.gov/pubmed/19470740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0005
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