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The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
Upon detection of antigen, CD4(+) T helper (Th) cells can differentiate into a number of effector types that tailor the immune response to different pathogens. Alternative Th1 and Th2 cell fates are specified by the transcription factors T-bet and GATA-3, respectively. Only a handful of target genes...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764903/ https://ncbi.nlm.nih.gov/pubmed/19805038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909357106 |
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