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Epstein-Barr virus LMP2A bypasses p53 inactivation in a MYC model of lymphomagenesis
Although Epstein-Barr virus (EBV) is linked to Burkitt's lymphoma (BL), the role of the virus in lymphomagenesis is unclear. LMP2A, encoded by EBV, can be detected in BL biopsies and has prosurvival functions. We generated mice expressing MYC and LMP2A in B cells. LMP2A/λ-MYC mice show greatly...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764894/ https://ncbi.nlm.nih.gov/pubmed/19815507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907994106 |
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