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Structural imperatives impose diverse evolutionary constraints on helical membrane proteins
The amino acid sequences of transmembrane regions of helical membrane proteins are highly constrained, diverging at slower rates than their extramembrane regions and than water-soluble proteins. Moreover, helical membrane proteins seem to fall into fewer families than water-soluble proteins. The rea...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764890/ https://ncbi.nlm.nih.gov/pubmed/19815527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906390106 |
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