Structure of a trimeric nucleoporin complex reveals alternate oligomerization states

The heptameric Nup84 complex constitutes an evolutionarily conserved building block of the nuclear pore complex. Here, we present the crystal structure of the heterotrimeric Sec13·Nup145C·Nup84 complex, the centerpiece of the heptamer, at 3.2-Å resolution. Nup84 forms a U-shaped α-helical solenoid d...

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Bibliografiset tiedot
Päätekijät: Nagy, Vivien, Hsia, Kuo-Chiang, Debler, Erik W., Kampmann, Martin, Davenport, Andrew M., Blobel, Günter, Hoelz, André
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2009
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764879/
https://ncbi.nlm.nih.gov/pubmed/19805193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909373106
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