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Image-based multiscale modeling predicts tissue-level and network-level fiber reorganization in stretched cell-compacted collagen gels

The mechanical environment plays an important role in cell signaling and tissue homeostasis. Unraveling connections between externally applied loads and the cellular response is often confounded by extracellular matrix (ECM) heterogeneity. Image-based multiscale models provide a foundation for exami...

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Detalhes bibliográficos
Main Authors: Sander, Edward A., Stylianopoulos, Triantafyllos, Tranquillo, Robert T., Barocas, Victor H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764876/
https://ncbi.nlm.nih.gov/pubmed/19805118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903716106
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