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Correlation of enzyme-inducing anticonvulsant use with outcome of patients with glioblastoma
BACKGROUND: Clinical trials involving patients with glioblastoma (GBM) distinguish cohorts who are treated with enzyme-inducing anticonvulsants (EIAC). Such anticonvulsants induce hepatic P450 microsomal enzymes, which accelerate the metabolism of certain chemotherapy and molecular targeted agents....
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Academy of Neurology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764724/ https://ncbi.nlm.nih.gov/pubmed/19822870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181bbfeca |
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