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Stable replication of the EBNA1/OriP-mediated baculovirus vector and its application to anti-HCV gene therapy

BACKGROUND: Hepatitis C virus (HCV) is one of the main causes of liver-related morbidity and mortality. Although combined interferon-α-ribavirin therapy is effective for about 50% of the patients with HCV, better therapies are needed and preventative vaccines have yet to be developed. Short-hairpin...

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Main Authors: Suzuki, Hitoshi, Matsumoto, Norihiko, Suzuki, Tomoyuki, Chang, Myint OO, Takaku, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764697/
https://ncbi.nlm.nih.gov/pubmed/19796392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-156
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