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EBNA1 distorts oriP, the Epstein-Barr virus latent replication origin.

The Epstein-Barr virus nuclear antigen 1 (EBNA1) protein binds and activates the latent replication origin (oriP) of the Epstein-Barr virus. We have been studying EBNA1 to determine how it activates replication at oriP. Here we demonstrate that upon binding of EBNA1 to oriP, two thymine residues bec...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Frappier, L, O'Donnell, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1310782/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.3.1786-1790.1992
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