Divergence of macrophage phagocytic and antimicrobial programs in leprosy

Effective innate immunity against many microbial pathogens requires macrophage programs that upregulate phagocytosis and direct antimicrobial pathways, two functions generally assumed to be coordinately regulated. Here the regulation of these key functions was investigated in human blood-derived mac...

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Autors principals: Montoya, Dennis, Cruz, Daniel, Teles, Rosane M.B., Lee, Delphine J., Ochoa, Maria Teresa, Krutzik, Stephan R., Chun, Rene, Schenk, Mirjam, Zhang, Xiaoran, Ferguson, Benjamin G., Burdick, Anne E., Sarno, Euzenir N., Rea, Thomas H., Hewison, Martin, Adams, John S., Cheng, Genhong, Modlin, Robert L.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764558/
https://ncbi.nlm.nih.gov/pubmed/19837374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2009.09.002
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