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Elevation of MMP-3 and MMP-9 in CSF and Blood in Patients with Severe Traumatic Brain Injury

OBJECTIVE: Traumatic brain injury (TBI) causes elevation of matrix metalloproteinases (MMPs), which are associated with neuroinflammation, blood-brain barrier (BBB) disruption, hemorrhage and cell death. We hypothesized that patients with TBI have an increase in MMPs in the ventricular cerebrospinal...

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Autori principali: Grossetete, Mark, Phelps, Jeremy, Arko, Leopold, Yonas, Howard, Rosenberg, Gary A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764327/
https://ncbi.nlm.nih.gov/pubmed/19834375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/01.NEU.0000351768.11363.48
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