Dosing Regimens of Cotrimoxazole (Trimethoprim-Sulfamethoxazole) for Melioidosis

Melioidosis is an infectious disease with a propensity for relapse, despite prolonged antibiotic eradication therapy for 12 to 20 weeks. A pharmacokinetic (PK) simulation study was performed to determine the optimal dosing of cotrimoxazole (trimethoprim-sulfamethoxazole [TMP-SMX]) used in current er...

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Autori principali: Cheng, Allen C., McBryde, Emma S., Wuthiekanun, Vanaporn, Chierakul, Wirongrong, Amornchai, Premjit, Day, Nicholas P. J., White, Nicholas J., Peacock, Sharon J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764189/
https://ncbi.nlm.nih.gov/pubmed/19620336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01301-08
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