Trimethoprim-sulfamethoxazole versus trimethoprim-sulfamethoxazole plus doxycycline as oral eradicative treatment for melioidosis (MERTH): a multicentre, double-blind, non-inferiority, randomised controlled trial

BACKGROUND: Melioidosis, an infectious disease caused by the Gram-negative bacillus Burkholderia pseudomallei, is difficult to cure. Antimicrobial treatment comprises intravenous drugs for at least 10 days, followed by oral drugs for at least 12 weeks. The standard oral regimen based on trial eviden...

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Asıl Yazarlar: Chetchotisakd, Ploenchan, Chierakul, Wirongrong, Chaowagul, Wipada, Anunnatsiri, Siriluck, Phimda, Kriangsak, Mootsikapun, Piroon, Chaisuksant, Seksan, Pilaikul, Jiraporn, Thinkhamrop, Bandit, Phiphitaporn, Sunchai, Susaengrat, Wattanachai, Toondee, Chalongchai, Wongrattanacheewin, Surasakdi, Wuthiekanun, Vanaporn, Chantratita, Narisara, Thaipadungpanit, Janjira, Day, Nicholas P, Limmathurotsakul, Direk, Peacock, Sharon J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2014
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939931/
https://ncbi.nlm.nih.gov/pubmed/24284287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(13)61951-0
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