Trimethoprim-sulfamethoxazole versus trimethoprim-sulfamethoxazole plus doxycycline as oral eradicative treatment for melioidosis (MERTH): a multicentre, double-blind, non-inferiority, randomised controlled trial

BACKGROUND: Melioidosis, an infectious disease caused by the Gram-negative bacillus Burkholderia pseudomallei, is difficult to cure. Antimicrobial treatment comprises intravenous drugs for at least 10 days, followed by oral drugs for at least 12 weeks. The standard oral regimen based on trial eviden...

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Main Authors: Chetchotisakd, Ploenchan, Chierakul, Wirongrong, Chaowagul, Wipada, Anunnatsiri, Siriluck, Phimda, Kriangsak, Mootsikapun, Piroon, Chaisuksant, Seksan, Pilaikul, Jiraporn, Thinkhamrop, Bandit, Phiphitaporn, Sunchai, Susaengrat, Wattanachai, Toondee, Chalongchai, Wongrattanacheewin, Surasakdi, Wuthiekanun, Vanaporn, Chantratita, Narisara, Thaipadungpanit, Janjira, Day, Nicholas P, Limmathurotsakul, Direk, Peacock, Sharon J
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2014
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Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939931/
https://ncbi.nlm.nih.gov/pubmed/24284287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(13)61951-0
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