Llwytho...

Novel Antimalarial Aminoquinolines: Heme Binding and Effects on Normal or Plasmodium falciparum-Parasitized Human Erythrocytes

Two new quinolizidinyl-alkyl derivatives of 7-chloro-4-aminoquinoline, named AM-1 and AP4b, which are highly effective in vitro against both the D10 (chloroquine [CQ] susceptible) and W2 (CQ resistant) strains of Plasmodium falciparum and in vivo in the rodent malaria model, have been studied for th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Omodeo-Salè, Fausta, Cortelezzi, Lucia, Basilico, Nicoletta, Casagrande, Manolo, Sparatore, Anna, Taramelli, Donatella
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764181/
https://ncbi.nlm.nih.gov/pubmed/19651905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00536-09
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