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On the Utilization of Energy Minimization to the Study of Ion Selectivity

The major pitfalls in studying ion selectivity in binding site models using energy minimization based methods are examined and discussed. It is shown that the properties derived from energy minimization are strongly configuration-dependent and that the results should be interpreted with caution. It...

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Библиографические подробности
Главные авторы: Yu, Haibo, Roux, Benoît
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764064/
https://ncbi.nlm.nih.gov/pubmed/19843443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.005
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