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Usa1 Protein Facilitates Substrate Ubiquitylation through Two Separate Domains

BACKGROUND: Defects in protein folding are recognized as the root of many neurodegenerative disorders. In the endoplasmic reticulum (ER), secretory proteins are subjected to a stringent quality control process to eliminate misfolded proteins by the ER-associated degradation (ERAD) pathway. A novel E...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Ikjin, Li, Yue, Muniz, Paulina, Rao, Hai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764048/
https://ncbi.nlm.nih.gov/pubmed/19898607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007604
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