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Usa1 Protein Facilitates Substrate Ubiquitylation through Two Separate Domains
BACKGROUND: Defects in protein folding are recognized as the root of many neurodegenerative disorders. In the endoplasmic reticulum (ER), secretory proteins are subjected to a stringent quality control process to eliminate misfolded proteins by the ER-associated degradation (ERAD) pathway. A novel E...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764048/ https://ncbi.nlm.nih.gov/pubmed/19898607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007604 |
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