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Life on the edge: telomeres and persistent DNA breaks converge at the nuclear periphery

Persistent DNA double-strand breaks and telomeres represent genomic hazards, as they can instigate inappropriate repair reactions. Two recent papers by Oza and colleagues (pp. 912–917) and Schober and colleagues (pp. 928–938) show that both types of DNA ends are sequestered from bulk DNA by Mps3, a...

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Bibliografiske detaljer
Hovedforfatter: Gartenberg, Marc R.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763515/
https://ncbi.nlm.nih.gov/pubmed/19417100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1805309
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