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Life on the edge: telomeres and persistent DNA breaks converge at the nuclear periphery
Persistent DNA double-strand breaks and telomeres represent genomic hazards, as they can instigate inappropriate repair reactions. Two recent papers by Oza and colleagues (pp. 912–917) and Schober and colleagues (pp. 928–938) show that both types of DNA ends are sequestered from bulk DNA by Mps3, a...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763515/ https://ncbi.nlm.nih.gov/pubmed/19417100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1805309 |
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