O-linked β-N-acetylglucosamine during hyperglycemia exerts both anti-inflammatory and pro-oxidative properties in the endothelial system

Elevated cellular levels of protein O-linked β-N-acetylglucosamine (O-GlcNAc) through hexosamine biosynthesis pathway (HBP) are suggested to contribute to cardiovascular adverse effects under chronic hyperglycemic condition associated with oxidative stress and inflammation. Conversely, enhancing O-G...

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Hauptverfasser: Rajapakse, Angana Gupta, Ming, Xiu-Fen, Carvas, João M, Yang, Zhihong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763244/
https://ncbi.nlm.nih.gov/pubmed/20592773
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