A Central Role for Induced Regulatory T Cells in Tolerance Induction in Experimental Colitis

In addition to thymus-derived or natural T regulatory (nT(reg)) cells, a second subset of induced T regulatory (iT(reg)) cells arises de novo from conventional CD4(+) T cells in the periphery. The function of iT(reg) cells in tolerance was examined in a CD45RB(high)CD4(+) T cell transfer model of co...

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Bibliographic Details
Main Authors: Haribhai, Dipica, Lin, Wen, Edwards, Brandon, Ziegelbauer, Jennifer, Salzman, Nita H., Carlson, Marc R., Li, Shun-Hwa, Simpson, Pippa M., Chatila, Talal A., Williams, Calvin B.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763205/
https://ncbi.nlm.nih.gov/pubmed/19265124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802535
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