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Butyrate and Vitamin D(3) Induce Transcriptional Attenuation at the Cyclin D1 Locus in Colonic Carcinoma Cells

In stimulating maturation of colonic carcinoma cells, the short chain fatty acid butyrate, and 1α, 25-dihydroxyvitamin D(3), were shown to attenuate transcription of the cyclin D1 gene, giving rise to truncated transcripts of this locus. Moreover, a sequence which is highly conserved in the human, m...

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Detalhes bibliográficos
Main Authors: Maier, Sandra, Daroqui, M. Cecilia, Scherer, Stefan, Roepcke, Stefan, Velcich, Anna, Shenoy, Shailesh M., Singer, Robert H., Augenlicht, Leonard H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763190/
https://ncbi.nlm.nih.gov/pubmed/19034928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21642
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