Activation of the Akt-NF-κB Pathway by Subtilase Cytotoxin through the ATF6 Branch of the Unfolded Protein Response

Shiga toxin has the potential to induce expression of inflammation-associated genes, although the underlying mechanisms are not well understood. We examined the effects of subtilase cytotoxin (SubAB), an AB(5) toxin produced by some Shiga toxigenic Escherichia coli, on the activation of NF-κB. SubAB...

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Main Authors: Yamazaki, Hiroaki, Hiramatsu, Nobuhiko, Hayakawa, Kunihiro, Tagawa, Yasuhiro, Okamura, Maro, Ogata, Ryouji, Huang, Tao, Nakajima, Shotaro, Yao, Jian, Paton, Adrienne W., Paton, James C., Kitamura, Masanori
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762936/
https://ncbi.nlm.nih.gov/pubmed/19561103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900017
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