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Microglial responses to dopamine in a cell culture model of Parkinson’s disease

Activated microglia appear to selectively attack dopamine (DA) neurons in the Parkinson’s disease (PD) substantia nigra. We investigated potential mechanisms using culture models. As targets, human SH-SY5Y cells were left undifferentiated, or were differentiated with retinoic acid (RA) or RA plus br...

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Hlavní autoři: Mastroeni, Diego, Grover, Andrew, Leonard, Brian, Joyce, Jeffrey N., Coleman, Paul D., Kozik, Brooke, Bellinger, Denise L., Rogers, Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762863/
https://ncbi.nlm.nih.gov/pubmed/18325635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.01.001
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