Microglial responses to dopamine in a cell culture model of Parkinson’s disease

Activated microglia appear to selectively attack dopamine (DA) neurons in the Parkinson’s disease (PD) substantia nigra. We investigated potential mechanisms using culture models. As targets, human SH-SY5Y cells were left undifferentiated, or were differentiated with retinoic acid (RA) or RA plus br...

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Detalhes bibliográficos
Main Authors: Mastroeni, Diego, Grover, Andrew, Leonard, Brian, Joyce, Jeffrey N., Coleman, Paul D., Kozik, Brooke, Bellinger, Denise L., Rogers, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762863/
https://ncbi.nlm.nih.gov/pubmed/18325635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.01.001
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