Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors’ anticancer efficacy

Lignende værker

• Enhancing mTOR-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation
  af: Wang, Xuerong, et al.
  Udgivet: (2008)
• Perifosine Inhibits mTOR Signaling through Facilitating Degradation of Major Components in the mTOR Axis and Induces Autophagy
  af: Fu, Lei, et al.
  Udgivet: (2009)
• Phase I and pharmacokinetic study of everolimus, an mTOR inhibitor, in combination with docetaxel for recurrent/refractory non-small cell lung cancer
  af: Ramalingam, Suresh S., et al.
  Udgivet: (2010)
• The Paradox of Akt-mTOR Interactions
  af: Vadlakonda, Lakshmipathi, et al.
  Udgivet: (2013)
• Modulation of Bax and mTOR for cancer therapeutics
  af: Li, Rui, et al.
  Udgivet: (2017)