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Efficient, Glucose Responsive, and Islet-Specific Transgene Expression by a Modified Rat Insulin Promoter

This study was done to improve efficiency and islet specificity of the rat insulin promoter (RIP). Various rat insulin promoter lengths were prepared and tested in vitro to drive luciferase reporter gene expression in INS1-cells, alpha-cells, acinar cells, ductal cells, and fibroblasts. The CMV prom...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chai, Renjie, Chen, Shuyuan, Ding, Jiahuan, Grayburn, Paul A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762485/
https://ncbi.nlm.nih.gov/pubmed/19727136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.114
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