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Rapid Development of Hypertension by Sorafenib: Toxicity or Target?

Blood pressure (BP) elevation is likely a pharmacodynamic marker of VEGF signaling pathway (VSP) inhibition and could be useful for optimizing safe and effective VSP inhibitor dosing. BP rises on the first day of treatment, facilitating design and interpretation of future trials aiming to correlate...

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Hlavní autoři: Humphreys, Benjamin D., Atkins, Michael B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762358/
https://ncbi.nlm.nih.gov/pubmed/19789317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1717
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