Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: A structural clue to amyloid assembly
Limited solubility and precipitation of amyloidogenic sequences such as the Alzheimer peptide (β-AP) are major obstacles to a molecular understanding of protein fibrillation and deposition processes. Here we have circumvented the solubility problem by stepwise engineering a β-AP homology into a solu...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
|---|---|
| Główni autorzy: | , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2000
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27622/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10944185/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.160086297 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|