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Protein Tyrosine Phosphatase Epsilon Regulates Integrin-mediated Podosome Stability in Osteoclasts by Activating Src

The nonreceptor isoform of tyrosine phosphatase epsilon (cyt-PTPe) supports osteoclast adhesion and activity in vivo, leading to increased bone mass in female mice lacking PTPe (EKO mice). The structure and organization of the podosomal adhesion structures of EKO osteoclasts are abnormal; the molecu...

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書目詳細資料
Main Authors: Granot-Attas, Shira, Luxenburg, Chen, Finkelshtein, Eynat, Elson, Ari
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762143/
https://ncbi.nlm.nih.gov/pubmed/19692574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-11-1158
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