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Structural and Spatial Determinants Regulating TC21 Activation by RasGRF Family Nucleotide Exchange Factors

RasGRF family guanine nucleotide exchange factors (GEFs) promote guanosine diphosphate (GDP)/guanosine triphosphate (GTP) exchange on several Ras GTPases, including H-Ras and TC21. Although the mechanisms controlling RasGRF function as an H-Ras exchange factor are relatively well characterized, litt...

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Autori principali: Calvo, Fernando, Crespo, Piero
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762140/
https://ncbi.nlm.nih.gov/pubmed/19692568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-03-0212
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