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Tyrosines in the Kinesin-5 head domain are necessary for phosphorylation by Wee1 and for mitotic spindle integrity
Mitotic spindle assembly and maintenance relies on Kinesin-5 motors that act as bipolar homotetramers to cross-link microtubules [1–5]. Kinesin-5 motors have been subject to extensive structure-function analysis [5], but the regulation of their activity in the context of mitotic progression remains...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762001/ https://ncbi.nlm.nih.gov/pubmed/19800237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.08.013 |
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