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Drosophila Wee1 Interacts with Members of the γTURC and Is Required for Proper Mitotic-Spindle Morphogenesis and Positioning
BACKGROUND: Wee1 kinases delay entry into mitosis by phosphorylating and inactivating cyclin-dependent kinase 1 (Cdk1). Loss of this activity in many systems, including Drosophila, leads to premature mitotic entry. RESULTS: We report here that Drosophila Wee1 (dwee1) mutant embryos show mitotic-spin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242738/ https://ncbi.nlm.nih.gov/pubmed/16139207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2005.07.031 |
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