Binge Drinking Upregulates Accumbens mGluR5–Homer2–PI3K Signaling: Functional Implications for Alcoholism

The glutamate receptor-associated protein Homer2 regulates alcohol-induced neuroplasticity within the nucleus accumbens (NAC), but the precise intracellular signaling cascades involved are not known. This study examined the role for NAC metabotropic glutamate receptor (mGluR)–Homer2–phosphatidylinos...

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Detalhes bibliográficos
Main Authors: Cozzoli, Debra K., Goulding, Scott P., Zhang, Ping Wu, Xiao, Bo, Hu, Jia-Hua, Ary, Alexis W., Obara, Ilona, Rahn, Alison, Abou-Ziab, Hoda, Tyrrel, Burgundy, Marini, Christina, Yoneyama, Naomi, Metten, Pamela, Snelling, Christopher, Dehoff, Marlin H., Crabbe, John C., Finn, Deborah A., Klugmann, Matthias, Worley, Paul F., Szumlinski, Karen K.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761716/
https://ncbi.nlm.nih.gov/pubmed/19587272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5900-08.2009
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