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Identification of human immunodeficiency virus-1 specific CD8(+) and CD4(+) T cell responses in perinatally infected infants and their mothers

BACKGROUND: There are few data describing the specificity, breadth and magnitude of T cell responses to HIV-1 in infancy. METHODS: HIV-specific CD8(+) and CD4(+) T cell responses to peptide pools representing Gag, Env, Pol, Nef and the regulatory regions (Reg) were simultaneously measured in 18 peri...

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Detalhes bibliográficos
Main Authors: Shalekoff, Sharon, Meddows-Taylor, Stephen, Gray, Glenda E., Sherman, Gayle G., Coovadia, Ashraf H., Kuhn, Louise, Tiemessen, Caroline T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761599/
https://ncbi.nlm.nih.gov/pubmed/19293686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e328329c784
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