Cutting Edge: Unusual NK Cell Responses to HIV-1 Peptides Are Associated with Protection against Maternal-Infant Transmission of HIV-1

Most infants exposed to HIV-1 in utero and at delivery do not acquire infection. We show that mothers and infants who have CD3-negative cells that respond to HIV-1 peptides are substantially less likely to transmit and acquire infection, respectively. The CD3-negative cells, shown to be NK cells, re...

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Auteurs principaux: Tiemessen, Caroline T., Shalekoff, Sharon, Meddows-Taylor, Stephen, Schramm, Diana B., Papathanasopoulos, Maria A., Gray, Glenda E., Sherman, Gayle G., Coovadia, Ashraf H., Kuhn, Louise
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841685/
https://ncbi.nlm.nih.gov/pubmed/19414742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900419
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