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A cellular defense pathway regulating transcription through poly(ADP-ribosyl)ation in response to DNA damage

DNA damage is known to trigger key cellular defense pathways such as those involved in DNA repair. Here we provide evidence for a previously unrecognized pathway regulating transcription in response to DNA damage and show that this regulation is mediated by the abundant nuclear enzyme poly(ADP-ribos...

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Detalhes bibliográficos
Main Authors: Vispé, Stéphane, Yung, Tetsu M. C., Ritchot, Janelle, Serizawa, Hiroaki, Satoh, Masahiko S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27615/
https://ncbi.nlm.nih.gov/pubmed/10944198
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