Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1

Plasma cells daily secrete their own mass in antibodies, which fold and assemble in the endoplasmic reticulum (ER). To reach these levels, cells require pERp1, a novel lymphocyte-specific small ER-resident protein, which attains expression levels as high as BiP when B cells differentiate into plasma...

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書誌詳細
主要な著者: van Anken, Eelco, Pena, Florentina, Hafkemeijer, Nicole, Christis, Chantal, Romijn, Edwin P., Grauschopf, Ulla, Oorschot, Viola M. J., Pertel, Thomas, Engels, Sander, Ora, Ari, Lástun, Viorica, Glockshuber, Rudi, Klumperman, Judith, Heck, Albert J. R., Luban, Jeremy, Braakman, Ineke
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761347/
https://ncbi.nlm.nih.gov/pubmed/19805154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903036106
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