Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1

Plasma cells daily secrete their own mass in antibodies, which fold and assemble in the endoplasmic reticulum (ER). To reach these levels, cells require pERp1, a novel lymphocyte-specific small ER-resident protein, which attains expression levels as high as BiP when B cells differentiate into plasma...

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Bibliografiset tiedot
Päätekijät: van Anken, Eelco, Pena, Florentina, Hafkemeijer, Nicole, Christis, Chantal, Romijn, Edwin P., Grauschopf, Ulla, Oorschot, Viola M. J., Pertel, Thomas, Engels, Sander, Ora, Ari, Lástun, Viorica, Glockshuber, Rudi, Klumperman, Judith, Heck, Albert J. R., Luban, Jeremy, Braakman, Ineke
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2009
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761347/
https://ncbi.nlm.nih.gov/pubmed/19805154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903036106
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