Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1

Plasma cells daily secrete their own mass in antibodies, which fold and assemble in the endoplasmic reticulum (ER). To reach these levels, cells require pERp1, a novel lymphocyte-specific small ER-resident protein, which attains expression levels as high as BiP when B cells differentiate into plasma...

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Detalhes bibliográficos
Main Authors: van Anken, Eelco, Pena, Florentina, Hafkemeijer, Nicole, Christis, Chantal, Romijn, Edwin P., Grauschopf, Ulla, Oorschot, Viola M. J., Pertel, Thomas, Engels, Sander, Ora, Ari, Lástun, Viorica, Glockshuber, Rudi, Klumperman, Judith, Heck, Albert J. R., Luban, Jeremy, Braakman, Ineke
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761347/
https://ncbi.nlm.nih.gov/pubmed/19805154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903036106
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