The human insulin receptor mRNA contains a functional internal ribosome entry segment

Regulation of mRNA translation is an important mechanism determining the level of expression of proteins in eukaryotic cells. Translation is most commonly initiated by cap-dependent scanning, but many eukaryotic mRNAs contain internal ribosome entry segments (IRESs), providing an alternative means o...

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Detalles Bibliográficos
Main Authors: Spriggs, Keith A., Cobbold, Laura C., Ridley, Simon H., Coldwell, Mark, Bottley, Andrew, Bushell, Martin, Willis, Anne E., Siddle, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761284/
https://ncbi.nlm.nih.gov/pubmed/19654240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp623
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