Nano positioning system reveals the course of upstream and nontemplate DNA within the RNA polymerase II elongation complex

Crystallographic studies of the RNA polymerase II (Pol II) elongation complex (EC) revealed the locations of downstream DNA and the DNA-RNA hybrid, but not the course of the nontemplate DNA strand in the transcription bubble and the upstream DNA duplex. Here we used single-molecule Fluorescence Reso...

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Bibliografiske detaljer
Main Authors: Andrecka, Joanna, Treutlein, Barbara, Arcusa, Maria Angeles Izquierdo, Muschielok, Adam, Lewis, Robert, Cheung, Alan C. M., Cramer, Patrick, Michaelis, Jens
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Nucleic Acid Enzymes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761271/
https://ncbi.nlm.nih.gov/pubmed/19620213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp601
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