Nano positioning system reveals the course of upstream and nontemplate DNA within the RNA polymerase II elongation complex

Crystallographic studies of the RNA polymerase II (Pol II) elongation complex (EC) revealed the locations of downstream DNA and the DNA-RNA hybrid, but not the course of the nontemplate DNA strand in the transcription bubble and the upstream DNA duplex. Here we used single-molecule Fluorescence Reso...

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Main Authors: Andrecka, Joanna, Treutlein, Barbara, Arcusa, Maria Angeles Izquierdo, Muschielok, Adam, Lewis, Robert, Cheung, Alan C. M., Cramer, Patrick, Michaelis, Jens
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Nucleic Acid Enzymes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761271/
https://ncbi.nlm.nih.gov/pubmed/19620213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp601
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