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Effects of Net Charge and the Number of Positively Charged Residues on the Biological Activity of Amphipathic α-Helical Cationic Antimicrobial Peptides

In our previous study, we utilized a 26-residue amphipathic α-helical antimicrobial peptide L-V13K (Chen et al., Antimicrob Agents Chemother 2007, 51, 1398−1406) as the framework to study the effects of peptide hydrophobicity on the mechanism of its antimicrobial action. In this study, we explored t...

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Detalles Bibliográficos
Main Authors: Jiang, Ziqing, Vasil, Adriana I., Hale, John D., Hancock, Robert E. W., Vasil, Michael L., Hodges, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761230/
https://ncbi.nlm.nih.gov/pubmed/18098173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.20911
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