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The duration of Fgf8 isthmic organizer expression is key to patterning different tectal-isthmo-cerebellum structures

The isthmic organizer and its key effector molecule, fibroblast growth factor 8 (Fgf8), have been cornerstones in studies of how organizing centers differentially pattern tissues. Studies have implicated different levels of Fgf8 signaling from the mid/hindbrain boundary (isthmus) as being responsibl...

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Autors principals: Sato, Tatsuya, Joyner, Alexandra L.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761110/
https://ncbi.nlm.nih.gov/pubmed/19793884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.041210
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