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Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy

Anemia is frequently observed in patients undergoing chemotherapy. Administration of darbepoetin alfa, a recombinant erythropoiesis-stimulating agent that has longer residence time than endogenous erythropoietin, to patients with chemotherapy-induced anemia (CIA) increases mean hemoglobin concentrat...

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Bibliografske podrobnosti
Main Authors: Agoram, Balaji, Heatherington, Anne C., Gastonguay, Marc R.
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761062/
https://ncbi.nlm.nih.gov/pubmed/17025273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080364
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