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New Cytochrome P450 1B1, 1C2 and 1D1 Genes in the Killifish Fundulus heteroclitus: Basal Expression and Response of Five Killifish CYP1s to the AHR Agonist PCB126

Knowledge of the complement of cytochrome P450 (CYP) genes is essential to understanding detoxification and bioactivation mechanisms for organic contaminants. We cloned three new CYP1 genes, CYP1B1, CYP1C2 and CYP1D1, from the killifish Fundulus heteroclitus, an important model in environmental toxi...

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Autors principals: Zanette, Juliano, Jenny, Matthew J., Goldstone, Jared V., Woodin, Bruce R., Watka, Lauren A., Bainy, Afonso C. D., Stegeman, John J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761021/
https://ncbi.nlm.nih.gov/pubmed/19515436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aquatox.2009.05.008
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